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ICD-10-PCS 2027 procedure code

3E03005Introduction of Other Antineoplastic into Peripheral Vein, Open Approach

✓ Valid for 2027

Short description: Introduce Oth Antineoplastic in Periph Vein, Open

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E03005

3E03005 is the ICD-10-PCS code for a introduction procedure on the peripheral vein using an open approach with antineoplastic (qualifier: other antineoplastic). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to other perfusion and injection or infusion of cancer chemotherapeutic substance, the ICD-9-CM procedure titles it maps to (39.97 and 99.25).

For a different body part, codes include 3E04005 (central vein), 3E05005 (peripheral artery), 3E06005 (central artery) and 3E0Q005 (cranial cavity and brain).

The same procedure with a different approach is coded 3E03305 (percutaneous).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
3Peripheral Vein
5. Approach
0Open

Cutting through the skin or mucous membrane and any other body layers necessary to expose the site of the procedure

6. Substance
0Antineoplastic

Includes: Amivantamab Monoclonal Antibody; Lurbinectedin; RYBREVANT (tm) (Amivantamab Monoclonal Antibody); ZEPZELCA(tm) (Lurbinectedin)

7. Qualifier
5Other Antineoplastic

Other versions of this procedure

Different approach

ICD-9-CM equivalent

Converter →
  • 39.97Other perfusionapproximate
  • 99.25Injection or infusion of cancer chemotherapeutic substanceapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E03005

Is 3E03005 a valid ICD-10-PCS code for 2027?

Yes. 3E03005 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E03005?

The CMS GEMs map 3E03005 to ICD-9-CM 39.97 (Other perfusion) and 99.25 (Injection or infusion of cancer chemotherapeutic substance).