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ICD-10-PCS 2027 procedure code

XW043G6Introduction of REGN-COV2 Monoclonal Antibody into Central Vein, Percutaneous Approach, New Technology Group 6

✓ Valid for 2027

Short description: Introduce REGN-COV2 in Central Vein, Perc, New Tech 6

Code last changed in FY2021 (effective October 1, 2020). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW043G6

XW043G6 is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with REGN-COV2 monoclonal antibody (qualifier: new technology group 6). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

For a different body part, codes include XW013G6 (subcutaneous tissue) and XW033G6 (peripheral vein).

With a different device, use XW04396 (odronextamab antineoplastic), XW043H6 (paclitaxel-coated balloon technology, one balloon) and XW043L6 (paclitaxel-coated balloon technology, four or more balloons).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2021, effective October 1, 2020.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
GREGN-COV2 Monoclonal Antibody

Includes: Casirivimab (REGN10933) and Imdevimab (REGN10987); Imdevimab (REGN10987) and Casirivimab (REGN10933)

7. Qualifier
6New Technology Group 6

Other versions of this procedure

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2021 (effective 10/1/2020): Added
  • No changes since FY2021.

Common questions about XW043G6

Is XW043G6 a valid ICD-10-PCS code for 2027?

Yes. XW043G6 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.