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ICD-10-PCS 2027 procedure code

XW043L6Introduction of CD24Fc Immunomodulator into Central Vein, Percutaneous Approach, New Technology Group 6

✓ Valid for 2027

Short description: Introduce CD24Fc in Central Vein, Perc, New Tech 6

Code last changed in FY2021 (effective October 1, 2020). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW043L6

XW043L6 is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with cd24fc immunomodulator (qualifier: new technology group 6). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

For a different body part, codes include XW033L6 (peripheral vein).

With a different device, use XW04396 (odronextamab antineoplastic), XW043G6 (vancomycin hydrochloride and tobramycin sulfate anti-infective, temporary irrigation spacer system) and XW043H6 (paclitaxel-coated balloon technology, one balloon).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2021, effective October 1, 2020.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
LCD24Fc Immunomodulator
7. Qualifier
6New Technology Group 6

Other versions of this procedure

Different body part

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2021 (effective 10/1/2020): Added
  • No changes since FY2021.

Common questions about XW043L6

Is XW043L6 a valid ICD-10-PCS code for 2027?

Yes. XW043L6 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.