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ICD-10-PCS 2027 procedure code

XW043RBIntroduction of Letetresgene Autoleucel into Central Vein, Percutaneous Approach, New Technology Group 11

✓ Valid for 2027Non-O.R. procedure

Short description: Introduce Letetresgene in Central Vein, Perc, New Tech 11

Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW043RB

XW043RB is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with letetresgene autoleucel (qualifier: new technology group 11). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

For a different body part, codes include XW033RB (peripheral vein).

With a different device, use XW0430B (alpha1-proteinase inhibitor), XW0431B (eladocagene exuparvovec), XW043FB (other new technology therapeutic substance), XW043PB (gentamicin-eluting bone void filler), XW043QB (iloprost) and XW043WB (AGN1 bone void filler).

It is a non-O.R. procedure that is part of the MS-DRG logic for DRG 018 (Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies), under the surgical category “Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies”.

It was added in FY2026, effective October 1, 2025.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
RLetetresgene Autoleucel

Includes: lete-cel

7. Qualifier
BNew Technology Group 11

Other versions of this procedure

Different body part

MS-DRG v44.0 grouping

All DRGs →

Surgical MS-DRGs this procedure can group to, depending on the principal diagnosis's MDC.

MDC PRE · Pre-MDC · Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2026 (effective 10/1/2025): Added
  • No changes since FY2026.

Common questions about XW043RB

Is XW043RB a valid ICD-10-PCS code for 2027?

Yes. XW043RB is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

Is XW043RB an O.R. procedure?

No. XW043RB is designated non-O.R. in MS-DRG v44.0.

What DRG does XW043RB group to?

Depending on the principal diagnosis, XW043RB can group to MS-DRG 018.