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ICD-10-PCS 2027 procedure code

XW0430BIntroduction of Alpha1-proteinase Inhibitor into Central Vein, Percutaneous Approach, New Technology Group 11

✓ Valid for 2027New for 2027

Short description: Introduce Alph-prtn Inhib in Central Vein, Perc, New Tech 11

Code last changed in FY2027 (effective October 1, 2026). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW0430B

XW0430B is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with alpha1-proteinase inhibitor (qualifier: new technology group 11). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

For a different body part, codes include XW0330B (peripheral vein).

With a different device, use XW0431B (eladocagene exuparvovec), XW043FB (other new technology therapeutic substance), XW043PB (gentamicin-eluting bone void filler), XW043QB (iloprost), XW043RB (letetresgene autoleucel) and XW043WB (AGN1 bone void filler).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2027, effective October 1, 2026.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
0Alpha1-proteinase Inhibitor

Includes: ZEMAIRA(R)

7. Qualifier
BNew Technology Group 11

Other versions of this procedure

Different body part

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2027 (effective 10/1/2026): Added

Common questions about XW0430B

Is XW0430B a valid ICD-10-PCS code for 2027?

Yes. XW0430B is valid for inpatient procedures from October 1, 2026 through September 30, 2027.