A50.49Other late congenital neurosyphilis

A50.49 is the ICD-10-CM diagnosis code for other late congenital neurosyphilis. It belongs to category A50 (congenital syphilis), block A50-A64 (infections with a predominantly sexual mode of transmission) and chapter 1 (certain infectious and parasitic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within A50.4, choose A50.49 (Other late congenital neurosyphilis) only when documentation doesn't support a more specific option: late congenital neurosyphilis, unspecified (A50.40), late congenital syphilitic meningitis (A50.41), late congenital syphilitic encephalitis (A50.42), late congenital syphilitic polyneuropathy (A50.43), late congenital syphilitic optic nerve atrophy (A50.44) and juvenile general paresis (A50.45).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 097 (Non-Bacterial Infection of Nervous System Except Viral Meningitis with MCC, relative weight 3.8226), DRG 098 (Non-Bacterial Infection of Nervous System Except Viral Meningitis with CC, relative weight 2.2706) and DRG 099 (Non-Bacterial Infection of Nervous System Except Viral Meningitis without CC/MCC, relative weight 1.5256), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 090.49 (other juvenile neurosyphilis).