ICD-10-CM 2027 diagnosis code

C25Malignant neoplasm of pancreas

Not billable — use a more specific code

C25 is a header code, so it can't be reported by itself. Choose one of the 8 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About C25

C25 is the ICD-10-CM diagnosis code for malignant neoplasm of pancreas. It belongs to block C15-C26 (malignant neoplasms of digestive organs) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 8 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: C25.0 (pancreas), C25.1 (pancreas), C25.2 (pancreas), C25.3 (duct), C25.4 (pancreas), C25.7 (pancreas), C25.8 (pancreas) and C25.9 (unspecified).

Use an additional code to identify: alcohol abuse and dependence (F10.-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under C25

Coding notes

Use additional codeAdd a secondary code to fully describe the condition

code to identify:
alcohol abuse and dependence (F10.-)

Code alsoTwo codes may be needed; sequencing depends on circumstances

if applicable exocrine pancreatic insufficiency (K86.81)

Notes that apply from higher levels

Instructions written at a parent level also apply to C25.

Broader instructions also apply from C15-C26 Malignant neoplasms of digestive organs and Chapter 2: Neoplasms.

Code history

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about C25

Is C25 billable?: No. C25 is a header code. Report one of its more specific subcodes instead.