ICD-10-CM 2027 diagnosis code
C25.2Malignant neoplasm of tail of pancreas
C25.2 is a valid, billable ICD-10-CM code for malignant neoplasm of tail of pancreas. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About C25.2
C25.2 is the ICD-10-CM diagnosis code for malignant neoplasm of tail of pancreas. It belongs to category C25 (malignant neoplasm of pancreas), block C15-C26 (malignant neoplasms of digestive organs) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within C25 (malignant neoplasm of pancreas), C25.2 is specifically for malignant neoplasm of tail of pancreas. Related codes cover head of pancreas (C25.0), body of pancreas (C25.1), pancreatic duct (C25.3), endocrine pancreas (C25.4), other parts of pancreas (C25.7), overlapping sites of pancreas (C25.8) and unspecified (C25.9).
Use an additional code to identify: alcohol abuse and dependence (F10.-).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 435 (Malignancy of Hepatobiliary System or Pancreas with MCC, relative weight 1.843), DRG 436 (Malignancy of Hepatobiliary System or Pancreas with CC, relative weight 1.1224) and DRG 437 (Malignancy of Hepatobiliary System or Pancreas without CC/MCC, relative weight 0.8081), in MDC 07 (Diseases and Disorders of the Hepatobiliary System and Pancreas), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 157.2 (malignant neoplasm of tail of pancreas).
Notes that apply from higher levels
Instructions written at a parent level also apply to C25.2.
Broader instructions also apply from C15-C26 Malignant neoplasms of digestive organs and Chapter 2: Neoplasms.
Table of Drugs & Neoplasms entries
- Neoplasm, neoplastic › pancreas › tail — Malignant Primary
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 07 · Diseases and Disorders of the Hepatobiliary System and Pancreas
ICD-9-CM equivalent
Converter →- 157.2Malignant neoplasm of tail of pancreasexact
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about C25.2
Is C25.2 billable?
- Yes. C25.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can C25.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict C25.2 as a principal diagnosis.
Is C25.2 a CC or MCC?
- C25.2 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.
What DRG does C25.2 group to?
- C25.2 is used in the MS-DRG v44.0 logic for MS-DRG 435 (Malignancy of Hepatobiliary System or Pancreas with MCC), MS-DRG 436 (Malignancy of Hepatobiliary System or Pancreas with CC) and MS-DRG 437 (Malignancy of Hepatobiliary System or Pancreas without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for C25.2?
- The CMS General Equivalence Mappings map C25.2 to ICD-9-CM 157.2.