ICD-10-CM 2027 diagnosis code
C78Secondary malignant neoplasm of respiratory and digestive organs
C78 is a header code, so it can't be reported by itself. Choose one of the 9 more specific codes beneath it.Short description: Secondary malignant neoplasm of resp and digestive organs
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About C78
C78 is the ICD-10-CM diagnosis code for secondary malignant neoplasm of respiratory and digestive organs. It belongs to block C76-C80 (malignant neoplasms of ill-defined, other secondary and unspecified sites) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 9 subcodes must be used instead.
To report this condition, pick the subcode that matches the documentation: C78.0 (lung), C78.1 (mediastinum), C78.2 (pleura), C78.3 (organs), C78.4 (intestine), C78.5 (rectum), C78.6 (peritoneum), C78.7 (duct) and 1 more.
Don't report C78 together with the conditions in its Excludes1 note: secondary carcinoid tumors of liver (C7B.02) and secondary carcinoid tumors of peritoneum (C7B.04).
The conditions in its Excludes2 note aren't part of C78, but may be coded alongside it if the patient has both: lymph node metastases (C77.0).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under C78
- C78.0Secondary malignant neoplasm of lung
- C78.1Secondary malignant neoplasm of mediastinumBillable
- C78.2Secondary malignant neoplasm of pleuraBillable
- C78.3Secondary malignant neoplasm of other and unspecified respiratory organs
- C78.4Secondary malignant neoplasm of small intestineBillable
- C78.5Secondary malignant neoplasm of large intestine and rectumBillable
- C78.6Secondary malignant neoplasm of retroperitoneum and peritoneumBillable
- C78.7Secondary malignant neoplasm of liver and intrahepatic bile ductBillable
- C78.8Secondary malignant neoplasm of other and unspecified digestive organs
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to C78.
Broader instructions also apply from Chapter 2: Neoplasms.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about C78
Is C78 billable?
- No. C78 is a header code. Report one of its more specific subcodes instead.