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ICD-10-CM 2027 diagnosis code

C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct

✓ Billable / specificCC — complication/comorbidity

C78.7 is a valid, billable ICD-10-CM code for secondary malignant neoplasm of liver and intrahepatic bile duct. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Secondary malig neoplasm of liver and intrahepatic bile duct

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About C78.7

C78.7 is the ICD-10-CM diagnosis code for secondary malignant neoplasm of liver and intrahepatic bile duct. It belongs to category C78 (secondary malignant neoplasm of respiratory and digestive organs), block C76-C80 (malignant neoplasms of ill-defined, other secondary and unspecified sites) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within C78 (secondary malignant neoplasm of respiratory and digestive organs), C78.7 is specifically for secondary malignant neoplasm of liver and intrahepatic bile duct. Related codes cover lung (C78.0), mediastinum (C78.1), pleura (C78.2), other and unspecified respiratory organs (C78.3), small intestine (C78.4), large intestine and rectum (C78.5), retroperitoneum and peritoneum (C78.6) and other and unspecified digestive organs (C78.8).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 435 (Malignancy of Hepatobiliary System or Pancreas with MCC, relative weight 1.843), DRG 436 (Malignancy of Hepatobiliary System or Pancreas with CC, relative weight 1.1224) and DRG 437 (Malignancy of Hepatobiliary System or Pancreas without CC/MCC, relative weight 0.8081), in MDC 07 (Diseases and Disorders of the Hepatobiliary System and Pancreas), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 197.7 (malignant neoplasm of liver, secondary) and 197.8 (secondary malignant neoplasm of other digestive organs and spleen).

Notes that apply from higher levels

Instructions written at a parent level also apply to C78.7.

› From C78 Secondary malignant neoplasm of respiratory and digestive organs
Excludes1
  • secondary carcinoid tumors of liver (C7B.02)
  • secondary carcinoid tumors of peritoneum (C7B.04)
Excludes2
  • lymph node metastases (C77.0)

Broader instructions also apply from Chapter 2: Neoplasms.

Table of Drugs & Neoplasms entries

Codes whose notes reference C78.7

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 197.7Malignant neoplasm of liver, secondaryapproximate
  • 197.8Secondary malignant neoplasm of other digestive organs and spleenapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about C78.7

Is C78.7 billable?

Yes. C78.7 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can C78.7 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict C78.7 as a principal diagnosis.

Is C78.7 a CC or MCC?

C78.7 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does C78.7 group to?

C78.7 is used in the MS-DRG v44.0 logic for MS-DRG 435 (Malignancy of Hepatobiliary System or Pancreas with MCC), MS-DRG 436 (Malignancy of Hepatobiliary System or Pancreas with CC) and MS-DRG 437 (Malignancy of Hepatobiliary System or Pancreas without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for C78.7?

The CMS General Equivalence Mappings map C78.7 to ICD-9-CM 197.7 and 197.8.