ICD-10-CM 2027 diagnosis code
C85.2Mediastinal (thymic) large B-cell lymphoma
C85.2 is a header code, so it can't be reported by itself. Choose one of the 11 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About C85.2
C85.2 is the ICD-10-CM diagnosis code for mediastinal (thymic) large B-cell lymphoma. It belongs to category C85 (other specified and unspecified types of non-Hodgkin lymphoma), block C81-C96 (malignant neoplasms of lymphoid, hematopoietic and related tissue) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 11 subcodes must be used instead.
Within C85 (other specified and unspecified types of non-Hodgkin lymphoma), C85.2 is specifically for mediastinal (thymic) large B-cell lymphoma. Related codes cover unspecified B-cell lymphoma (C85.1), other specified types of non-Hodgkin lymphoma (C85.8) and Non-Hodgkin lymphoma, unspecified (C85.9).
To report this condition, pick the subcode that matches the documentation: C85.20 (unspecified site), C85.21 (lymph nodes of head, face, and neck), C85.22 (intrathoracic lymph nodes), C85.23 (intra-abdominal lymph nodes), C85.24 (lymph nodes of axilla and upper limb), C85.25 (lymph nodes of inguinal region and lower limb), C85.26 (intrapelvic lymph nodes), C85.27 (spleen) and 3 more.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under C85.2
- C85.20Mediastinal (thymic) large B-cell lymphoma, unspecified siteBillable
- C85.21Mediastinal (thymic) large B-cell lymphoma, lymph nodes of head, face, and neckBillable
- C85.22Mediastinal (thymic) large B-cell lymphoma, intrathoracic lymph nodesBillable
- C85.23Mediastinal (thymic) large B-cell lymphoma, intra-abdominal lymph nodesBillable
- C85.24Mediastinal (thymic) large B-cell lymphoma, lymph nodes of axilla and upper limbBillable
- C85.25Mediastinal (thymic) large B-cell lymphoma, lymph nodes of inguinal region and lower limbBillable
- C85.26Mediastinal (thymic) large B-cell lymphoma, intrapelvic lymph nodesBillable
- C85.27Mediastinal (thymic) large B-cell lymphoma, spleenBillable
- C85.28Mediastinal (thymic) large B-cell lymphoma, lymph nodes of multiple sitesBillable
- C85.29Mediastinal (thymic) large B-cell lymphoma, extranodal and solid organ sitesBillable
- C85.2AMediastinal (thymic) large B-cell lymphoma, in remissionBillable
Notes that apply from higher levels
Instructions written at a parent level also apply to C85.2.
Broader instructions also apply from C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue and Chapter 2: Neoplasms.
Alphabetic index entries
1 entriesTerms in the official ICD-10-CM index that lead to C85.2.
Codes whose notes reference C85.2
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about C85.2
Is C85.2 billable?
- No. C85.2 is a header code. Report one of its more specific subcodes instead.