C83.3Diffuse large B-cell lymphoma

C83.3 is the ICD-10-CM diagnosis code for diffuse large B-cell lymphoma. It belongs to category C83 (non-follicular lymphoma), block C81-C96 (malignant neoplasms of lymphoid, hematopoietic and related tissue) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 11 subcodes must be used instead.

Within C83 (non-follicular lymphoma), C83.3 is specifically for diffuse large B-cell lymphoma. Related codes cover small cell B-cell lymphoma (C83.0), Mantle cell lymphoma (C83.1), lymphoblastic (diffuse) lymphoma (C83.5), Burkitt lymphoma (C83.7), other non-follicular lymphoma (C83.8) and non-follicular (diffuse) lymphoma, unspecified (C83.9).

To report this condition, pick the subcode that matches the documentation: C83.30 (unspecified site), C83.31 (lymph nodes of head, face, and neck), C83.32 (intrathoracic lymph nodes), C83.33 (intra-abdominal lymph nodes), C83.34 (lymph nodes of axilla and upper limb), C83.35 (lymph nodes of inguinal region and lower limb), C83.36 (intrapelvic lymph nodes), C83.37 (spleen) and 3 more.

Don't report C83.3 together with the conditions in its Excludes1 note: mediastinal (thymic) large B-cell lymphoma (C85.2-) and mature T/NK-cell lymphomas (C84.-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.