Skip to content
Dx

ICD-10-CM 2027 diagnosis code

D68.021Von Willebrand disease, type 2B

✓ Billable / specificCC — complication/comorbidity

D68.021 is a valid, billable ICD-10-CM code for von willebrand disease, type 2b. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code last changed in FY2023 (effective October 1, 2022). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D68.021

D68.021 is the ICD-10-CM diagnosis code for von Willebrand disease, type 2B. It belongs to category D68 (other coagulation defects), block D65-D69 (coagulation defects, purpura and other hemorrhagic conditions) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within D68.02 (von Willebrand disease, type 2), D68.021 is specifically for von Willebrand disease, type 2B. Related codes cover A (D68.020), M (D68.022), N (D68.023) and unspecified (D68.029).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 813 (Coagulation Disorders, relative weight 1.5257), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2023, effective October 1, 2022.

Coding notes

Applicable toConditions and synonyms classified to this code
  • Qualitative defects of von Willebrand factor with high-molecular-weight von Willebrand factor loss
  • Qualitative defects of von Willebrand factor with hyper-adhesive forms
  • Qualitative defects of von Willebrand factor with increased affinity for platelet glycoprotein lb

Notes that apply from higher levels

Instructions written at a parent level also apply to D68.021.

› From D68.0 Von Willebrand disease
Excludes1
  • capillary fragility (hereditary) (D69.8)
  • factor VIII deficiency NOS (D66)
  • factor VIII deficiency with functional defect (D66)
› From D68 Other coagulation defects
Excludes1
  • abnormal coagulation profile NOS (R79.1)
Excludes2
  • coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1)
  • coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)

Broader instructions also apply from Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.

Alphabetic index entries

4 entries

Terms in the official ICD-10-CM index that lead to D68.021.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 16 · Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2023 (effective 10/1/2022): Added
  • No changes since FY2023.

Common questions about D68.021

Is D68.021 billable?

Yes. D68.021 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D68.021 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D68.021 as a principal diagnosis.

Is D68.021 a CC or MCC?

D68.021 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does D68.021 group to?

D68.021 is used in the MS-DRG v44.0 logic for MS-DRG 813 (Coagulation Disorders). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.