ICD-10-CM 2027 diagnosis code
E09.22Drug or chemical induced diabetes mellitus with diabetic chronic kidney disease
E09.22 is a valid, billable ICD-10-CM code for drug or chemical induced diabetes mellitus with diabetic chronic kidney disease. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Drug/chem diabetes w diabetic chronic kidney disease
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About E09.22
E09.22 is the ICD-10-CM diagnosis code for drug or chemical induced diabetes mellitus with diabetic chronic kidney disease. It belongs to category E09 (drug or chemical induced diabetes mellitus), block E08-E13 (diabetes mellitus) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within E09.2 (drug or chemical induced diabetes mellitus with kidney complications), E09.22 is specifically for drug or chemical induced diabetes mellitus with diabetic chronic kidney disease. Related codes cover diabetic nephropathy (E09.21) and other diabetic kidney complication (E09.29).
Code first: poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4).
Use an additional code to identify stage of chronic kidney disease (N18.1-N18.6). Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). Use an additional code to identify control using: injectable non-insulin antidiabetic drugs (Z79.85), insulin (Z79.4), oral antidiabetic drugs (Z79.84) and oral hypoglycemic drugs (Z79.84).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant, relative weight 5.5146), DRG 010 (Pancreas or Islet Cell Transplant, relative weight 7.5259), DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis, relative weight 7.5493), DRG 673 (Other Kidney and Urinary Tract Procedures with MCC, relative weight 4.2525), DRG 674 (Other Kidney and Urinary Tract Procedures with CC, relative weight 2.2504), DRG 675 (Other Kidney and Urinary Tract Procedures without CC/MCC, relative weight 1.5887) and 3 more, in Pre-MDC and MDC 11 (Diseases and Disorders of the Kidney and Urinary Tract), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 249.40 (secondary diabetes mellitus with renal manifestations, not stated as uncontrolled, or unspecified), 581.81 (nephrotic syndrome in diseases classified elsewhere) and 583.81 (nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere).
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to E09.22.
› From E09 Drug or chemical induced diabetes mellitus
- diabetes mellitus due to underlying condition (E08.-)
- gestational diabetes (O24.4-)
- neonatal diabetes mellitus (P70.2)
- postpancreatectomy diabetes mellitus (E13.-)
- postprocedural diabetes mellitus (E13.-)
- secondary diabetes mellitus NEC (E13.-)
- type 1 diabetes mellitus (E10.-)
- type 2 diabetes mellitus (E11.-)
Broader instructions also apply from Chapter 4: Endocrine, nutritional and metabolic diseases.
Alphabetic index entries
1 entriesTerms in the official ICD-10-CM index that lead to E09.22.
Codes whose notes reference E09.22
- N18Code first
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC PRE · Pre-MDC
MDC PRE · Pre-MDC
MDC PRE · Pre-MDC
MDC 11 · Diseases and Disorders of the Kidney and Urinary Tract
MDC 11 · Diseases and Disorders of the Kidney and Urinary Tract
ICD-9-CM equivalent
Converter →- 249.40Secondary diabetes mellitus with renal manifestations, not stated as uncontrolled, or unspecifiedapproximate, combination
- 581.81Nephrotic syndrome in diseases classified elsewhereapproximate, combination
- 583.81Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhereapproximate, combination
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about E09.22
Is E09.22 billable?
- Yes. E09.22 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E09.22 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E09.22 as a principal diagnosis.
Is E09.22 a CC or MCC?
- No. E09.22 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does E09.22 group to?
- E09.22 is used in the MS-DRG v44.0 logic for MS-DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant), MS-DRG 010 (Pancreas or Islet Cell Transplant), MS-DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis), MS-DRG 673 (Other Kidney and Urinary Tract Procedures with MCC), MS-DRG 674 (Other Kidney and Urinary Tract Procedures with CC), MS-DRG 675 (Other Kidney and Urinary Tract Procedures without CC/MCC) and 3 more. Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for E09.22?
- The CMS General Equivalence Mappings map E09.22 to ICD-9-CM 249.40, 581.81 and 583.81.