ICD-10-CM 2027 diagnosis code
E25.8Other adrenogenital disorders
E25.8 is a valid, billable ICD-10-CM code for other adrenogenital disorders. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About E25.8
E25.8 is the ICD-10-CM diagnosis code for other adrenogenital disorders. It belongs to category E25 (adrenogenital disorders), block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within E25, choose E25.8 (Other adrenogenital disorders) only when documentation doesn't support a more specific option: congenital adrenogenital disorders associated with enzyme deficiency (E25.0) and adrenogenital disorder, unspecified (E25.9).
Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 255.2 (adrenogenital disorders).
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to E25.8.
› From E25 Adrenogenital disorders
- adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
- Female adrenal pseudohermaphroditism
- Female heterosexual precocious pseudopuberty
- Male isosexual precocious pseudopuberty
- Male macrogenitosomia praecox
- Male sexual precocity with adrenal hyperplasia
- Male virilization (female)
Broader instructions also apply from E20-E35 Disorders of other endocrine glands and Chapter 4: Endocrine, nutritional and metabolic diseases.
Alphabetic index entries
11 entriesTerms in the official ICD-10-CM index that lead to E25.8.
- Adrenogenital syndrome › acquired
- Disorder (of) › adrenogenital › drug-induced
- Disorder (of) › adrenogenital › iatrogenic
- Disorder (of) › adrenogenital › idiopathic
- Pseudohermaphroditism › adrenal
- Pseudohermaphroditism › female › with adrenocortical disorder
- Pseudohermaphroditism › male › with › adrenocortical disorder
- Pseudohermaphroditism › male › adrenal
- Pseudopuberty, precocious › female heterosexual
- Pseudopuberty, precocious › male isosexual
- Puberty (development state) › premature › due to › adrenal cortical hyperfunction
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 10 · Endocrine, Nutritional and Metabolic Diseases and Disorders
ICD-9-CM equivalent
Converter →- 255.2Adrenogenital disordersapproximate
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about E25.8
Is E25.8 billable?
- Yes. E25.8 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E25.8 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E25.8 as a principal diagnosis.
Is E25.8 a CC or MCC?
- No. E25.8 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does E25.8 group to?
- E25.8 is used in the MS-DRG v44.0 logic for MS-DRG 643 (Endocrine Disorders with MCC), MS-DRG 644 (Endocrine Disorders with CC) and MS-DRG 645 (Endocrine Disorders without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for E25.8?
- The CMS General Equivalence Mappings map E25.8 to ICD-9-CM 255.2.