E34.2Ectopic hormone secretion, not elsewhere classified

E34.2 is the ICD-10-CM diagnosis code for ectopic hormone secretion, not elsewhere classified. It belongs to category E34 (other endocrine disorders), block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E34 (other endocrine disorders), E34.2 is specifically for ectopic hormone secretion, not elsewhere classified. Related codes cover carcinoid syndrome (E34.0), other hypersecretion of intestinal hormones (E34.1), short stature due to endocrine disorder (E34.3), constitutional tall stature (E34.4), androgen insensitivity syndrome (E34.5), other specified endocrine disorders (E34.8) and endocrine disorder, unspecified (E34.9).

Don't report E34.2 together with the conditions in its Excludes1 note: ectopic ACTH syndrome (E24.3).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 259.3 (ectopic hormone secretion, not elsewhere classified).