ICD-10-CM 2027 diagnosis code

E53Deficiency of other B group vitamins

Not billable — use a more specific code

E53 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E53

E53 is the ICD-10-CM diagnosis code for deficiency of other B group vitamins. It belongs to block E50-E64 (other nutritional deficiencies) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: E53.0 (deficiency), E53.1 (deficiency), E53.8 (vitamins) and E53.9 (unspecified).

Don't report E53 together with the conditions in its Excludes1 note: sequelae of vitamin B deficiency (E64.8).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under E53

Coding notes

Excludes1Not coded here — never report together with this code

sequelae of vitamin B deficiency (E64.8)

Notes that apply from higher levels

Instructions written at a parent level also apply to E53.

Broader instructions also apply from E50-E64 Other nutritional deficiencies and Chapter 4: Endocrine, nutritional and metabolic diseases.

Codes whose notes reference E53

D51Excludes2
F06.7Code first
G32.8Code first

Code history

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about E53

Is E53 billable?: No. E53 is a header code. Report one of its more specific subcodes instead.