E53.8Deficiency of other specified B group vitamins

E53.8 is the ICD-10-CM diagnosis code for deficiency of other specified B group vitamins. It belongs to category E53 (deficiency of other B group vitamins), block E50-E64 (other nutritional deficiencies) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E53, choose E53.8 (Deficiency of other specified B group vitamins) only when documentation doesn't support a more specific option: Riboflavin deficiency (E53.0), Pyridoxine deficiency (E53.1) and vitamin B deficiency, unspecified (E53.9).

Don't report E53.8 together with the conditions in its Excludes1 note: folate deficiency anemia (D52.-).

The conditions in its Excludes2 note aren't part of E53.8, but may be coded alongside it if the patient has both: vitamin B12 deficiency anemia (D51.-).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 640 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC, relative weight 1.3395) and DRG 641 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC, relative weight 0.7865), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 266.2 (other B-complex deficiencies).