F07.0Personality change due to known physiological condition

F07.0 is the ICD-10-CM diagnosis code for personality change due to known physiological condition. It belongs to category F07 (personality and behavioral disorders due to known physiological condition), block F01-F09 (mental disorders due to known physiological conditions) and chapter 5 (mental, Behavioral and Neurodevelopmental disorders). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within F07 (personality and behavioral disorders due to known physiological condition), F07.0 is specifically for personality change due to known physiological condition. Related codes cover other personality and behavioral disorders due to known physiological condition (F07.8) and unspecified personality and behavioral disorder due to known physiological condition (F07.9).

Don't report F07.0 together with the conditions in its Excludes1 note: mild cognitive impairment (G31.84), postconcussional syndrome (F07.81), postencephalitic syndrome (F07.89) and signs and symptoms involving emotional state (R45.-).

The conditions in its Excludes2 note aren't part of F07.0, but may be coded alongside it if the patient has both: specific personality disorder (F60.-).

Code first: the underlying physiological condition.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 884 (Organic Disturbances and Intellectual Disability, relative weight 1.6001), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 310.0 (frontal lobe syndrome) and 310.1 (personality change due to conditions classified elsewhere).