ICD-10-CM 2027 diagnosis code
F19.22Other psychoactive substance dependence with intoxication
F19.22 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About F19.22
F19.22 is the ICD-10-CM diagnosis code for other psychoactive substance dependence with intoxication. It belongs to category F19 (other psychoactive substance related disorders), block F10-F19 (mental and behavioral disorders due to psychoactive substance use) and chapter 5 (mental, Behavioral and Neurodevelopmental disorders). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.
Within F19.2 (other psychoactive substance dependence), F19.22 is specifically for other psychoactive substance dependence with intoxication. Related codes cover uncomplicated (F19.20), in remission (F19.21), with withdrawal (F19.23), with psychoactive substance-induced mood disorder (F19.24), with psychoactive substance-induced psychotic disorder (F19.25), with psychoactive substance-induced persisting amnestic disorder (F19.26), with psychoactive substance-induced persisting dementia (F19.27), with other psychoactive substance-induced disorders (F19.28) and 1 more.
To report this condition, pick the subcode that matches the documentation: F19.220 (uncomplicated), F19.221 (delirium), F19.222 (with perceptual disturbance) and F19.229 (unspecified).
Don't report F19.22 together with the conditions in its Excludes1 note: other psychoactive substance dependence with withdrawal (F19.23-).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under F19.22
- F19.220Other psychoactive substance dependence with intoxication, uncomplicatedBillable
- F19.221Other psychoactive substance dependence with intoxication deliriumBillable
- F19.222Other psychoactive substance dependence with intoxication with perceptual disturbanceBillable
- F19.229Other psychoactive substance dependence with intoxication, unspecifiedBillable
Coding notes
- other psychoactive substance dependence with withdrawal (F19.23-)
Notes that apply from higher levels
Instructions written at a parent level also apply to F19.22.
› From F19 Other psychoactive substance related disorders
- polysubstance drug use (indiscriminate drug use)
Broader instructions also apply from Chapter 5: Mental, Behavioral and Neurodevelopmental disorders.
Codes whose notes reference F19.22
- F19.23Excludes1
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about F19.22
Is F19.22 billable?
- No. F19.22 is a header code. Report one of its more specific subcodes instead.