ICD-10-CM 2027 diagnosis code
F19.28Other psychoactive substance dependence with other psychoactive substance-induced disorders
F19.28 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.Short description: Oth psychoactive substance dependence w oth disorders
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About F19.28
F19.28 is the ICD-10-CM diagnosis code for other psychoactive substance dependence with other psychoactive substance-induced disorders. It belongs to category F19 (other psychoactive substance related disorders), block F10-F19 (mental and behavioral disorders due to psychoactive substance use) and chapter 5 (mental, Behavioral and Neurodevelopmental disorders). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.
Within F19.2, choose F19.28 (with other psychoactive substance-induced disorders) only when documentation doesn't support a more specific option: uncomplicated (F19.20), in remission (F19.21), with intoxication (F19.22), with withdrawal (F19.23), with psychoactive substance-induced mood disorder (F19.24), with psychoactive substance-induced psychotic disorder (F19.25), with psychoactive substance-induced persisting amnestic disorder (F19.26), with psychoactive substance-induced persisting dementia (F19.27) and 1 more.
To report this condition, pick the subcode that matches the documentation: F19.280 (disorder), F19.281 (dysfunction), F19.282 (disorder) and F19.288 (disorder).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under F19.28
- F19.280Other psychoactive substance dependence with psychoactive substance-induced anxiety disorderBillable
- F19.281Other psychoactive substance dependence with psychoactive substance-induced sexual dysfunctionBillable
- F19.282Other psychoactive substance dependence with psychoactive substance-induced sleep disorderBillable
- F19.288Other psychoactive substance dependence with other psychoactive substance-induced disorderBillable
Notes that apply from higher levels
Instructions written at a parent level also apply to F19.28.
› From F19 Other psychoactive substance related disorders
- polysubstance drug use (indiscriminate drug use)
Broader instructions also apply from Chapter 5: Mental, Behavioral and Neurodevelopmental disorders.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about F19.28
Is F19.28 billable?
- No. F19.28 is a header code. Report one of its more specific subcodes instead.