Skip to content
Dx

ICD-10-CM 2027 diagnosis code

F19.99Other psychoactive substance use, unspecified with unspecified psychoactive substance-induced disorder

✓ Billable / specific

F19.99 is a valid, billable ICD-10-CM code for other psychoactive substance use, unspecified with unspecified psychoactive substance-induced disorder. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Oth psychoactive substance use, unsp w unsp disorder

Looking up by condition? See ICD-10 code for Misuse of drugs.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About F19.99

F19.99 is the ICD-10-CM diagnosis code for other psychoactive substance use, unspecified with unspecified psychoactive substance-induced disorder. It belongs to category F19 (other psychoactive substance related disorders), block F10-F19 (mental and behavioral disorders due to psychoactive substance use) and chapter 5 (mental, Behavioral and Neurodevelopmental disorders). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within F19.9, choose F19.99 (with unspecified psychoactive substance-induced disorder) only when documentation doesn't support a more specific option: uncomplicated (F19.90), in remission (F19.91), with intoxication (F19.92), with withdrawal (F19.93), with psychoactive substance-induced mood disorder (F19.94), with psychoactive substance-induced psychotic disorder (F19.95), with psychoactive substance-induced persisting amnestic disorder (F19.96), with psychoactive substance-induced persisting dementia (F19.97) and 1 more.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 894 (Alcohol, Drug Abuse or Dependence, Left AMA, relative weight 0.6275), DRG 895 (Alcohol, Drug Abuse or Dependence with Rehabilitation Therapy, relative weight 1.4266), DRG 896 (Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy with MCC, relative weight 1.6617) and DRG 897 (Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy without MCC, relative weight 0.8584), in MDC 20 (Alcohol/Drug Use and Alcohol/Drug Induced Organic Mental Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 292.9 (unspecified drug-induced mental disorder).

Notes that apply from higher levels

Instructions written at a parent level also apply to F19.99.

› From F19.9 Other psychoactive substance use, unspecified
Excludes1
  • other psychoactive substance abuse (F19.1-)
  • other psychoactive substance dependence (F19.2-)
› From F19 Other psychoactive substance related disorders
Includes
  • polysubstance drug use (indiscriminate drug use)

Broader instructions also apply from Chapter 5: Mental, Behavioral and Neurodevelopmental disorders.

Alphabetic index entries

3 entries

Terms in the official ICD-10-CM index that lead to F19.99.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 292.9Unspecified drug-induced mental disorderapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about F19.99

Is F19.99 billable?

Yes. F19.99 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can F19.99 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict F19.99 as a principal diagnosis.

Is F19.99 a CC or MCC?

No. F19.99 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does F19.99 group to?

F19.99 is used in the MS-DRG v44.0 logic for MS-DRG 894 (Alcohol, Drug Abuse or Dependence, Left AMA), MS-DRG 895 (Alcohol, Drug Abuse or Dependence with Rehabilitation Therapy), MS-DRG 896 (Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy with MCC) and MS-DRG 897 (Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for F19.99?

The CMS General Equivalence Mappings map F19.99 to ICD-9-CM 292.9.