ICD-10-CM 2027 diagnosis code
F32.81Premenstrual dysphoric disorder
F32.81 is a valid, billable ICD-10-CM code for premenstrual dysphoric disorder. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Code last changed in FY2017 (effective October 1, 2016). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About F32.81
F32.81 is the ICD-10-CM diagnosis code for Premenstrual dysphoric disorder. It belongs to category F32 (depressive episode), block F30-F39 (mood [affective] disorders) and chapter 5 (mental, Behavioral and Neurodevelopmental disorders). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within F32.8 (other depressive episodes), F32.81 is specifically for Premenstrual dysphoric disorder. Related codes cover other specified depressive episodes (F32.89).
Don't report F32.81 together with the conditions in its Excludes1 note: premenstrual tension syndrome (N94.3).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 885 (Psychoses, relative weight 1.3901), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It is on the CMS list of diagnoses consistent only with female patients (the sex-conflict edit itself was retired in FY2025).
It was added in FY2017, effective October 1, 2016.
Before ICD-10, this condition was coded in ICD-9-CM as 625.4 (Premenstrual tension syndromes).
Coding notes
- premenstrual tension syndrome (N94.3)
Notes that apply from higher levels
Instructions written at a parent level also apply to F32.81.
› From F32 Depressive episode
- single episode of agitated depression
- single episode of depressive reaction
- single episode of major depression
- single episode of psychogenic depression
- single episode of reactive depression
- single episode of vital depression
- adjustment disorder (F43.2)
Broader instructions also apply from Chapter 5: Mental, Behavioral and Neurodevelopmental disorders.
Alphabetic index entries
3 entriesTerms in the official ICD-10-CM index that lead to F32.81.
Codes whose notes reference F32.81
- N94.3Excludes1
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 19 · Mental Diseases and Disorders
ICD-9-CM equivalent
Converter →- 625.4Premenstrual tension syndromesapproximate
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2017 (effective 10/1/2016): Added
- No changes since FY2017.
Common questions about F32.81
Is F32.81 billable?
- Yes. F32.81 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can F32.81 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict F32.81 as a principal diagnosis.
Is F32.81 a CC or MCC?
- No. F32.81 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does F32.81 group to?
- F32.81 is used in the MS-DRG v44.0 logic for MS-DRG 885 (Psychoses). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for F32.81?
- The CMS General Equivalence Mappings map F32.81 to ICD-9-CM 625.4.