ICD-10-CM 2027 diagnosis code
G31.86Alexander disease
G31.86 is a valid, billable ICD-10-CM code for alexander disease. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Code last changed in FY2024 (effective October 1, 2023). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About G31.86
G31.86 is the ICD-10-CM diagnosis code for Alexander disease. It belongs to category G31 (other degenerative diseases of nervous system, not elsewhere classified), block G30-G32 (other degenerative diseases of the nervous system) and chapter 6 (diseases of the nervous system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within G31.8 (other specified degenerative diseases of nervous system), G31.86 is specifically for Alexander disease. Related codes cover leukodystrophy, unspecified (G31.80), Alpers disease (G31.81), Leigh's disease (G31.82), neurocognitive disorder with Lewy bodies (G31.83), mild cognitive impairment of uncertain or unknown etiology (G31.84), Corticobasal degeneration (G31.85), primary progressive apraxia of speech (G31.87) and other specified degenerative diseases of nervous system (G31.89).
Use an additional code, if applicable, for codes G31.0-G31.83, G31.85-G31.9, to identify: dementia with anxiety (F02.84, F02.A4, F02.B4, F02.C4), dementia with behavioral disturbance (F02.81-, F02.A1-, F02.B1-, F02.C1-), dementia with mood disturbance (F02.83, F02.A3, F02.B3, F02.C3), dementia with psychotic disturbance (F02.82, F02.A2, F02.B2, F02.C2), dementia without behavioral disturbance (F02.80, F02.A0, F02.B0, F02.C0) and 1 more.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 056 (Degenerative Nervous System Disorders with MCC, relative weight 2.2655) and DRG 057 (Degenerative Nervous System Disorders without MCC, relative weight 1.2838), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It was added in FY2024, effective October 1, 2023.
Notes that apply from higher levels
Instructions written at a parent level also apply to G31.86.
› From G31 Other degenerative diseases of nervous system, not elsewhere classified
- Reye's syndrome (G93.7)
- code, if applicable, for codes G31.0-G31.83, G31.85-G31.9, to identify:
- dementia with anxiety (F02.84, F02.A4, F02.B4, F02.C4)
- dementia with behavioral disturbance (F02.81-, F02.A1-, F02.B1-, F02.C1-)
- dementia with mood disturbance (F02.83, F02.A3, F02.B3, F02.C3)
- dementia with psychotic disturbance (F02.82, F02.A2, F02.B2, F02.C2)
- dementia without behavioral disturbance (F02.80, F02.A0, F02.B0, F02.C0)
- mild neurocognitive disorder due to known physiological condition (F06.7-)
Broader instructions also apply from Chapter 6: Diseases of the nervous system.
Alphabetic index entries
1 entriesTerms in the official ICD-10-CM index that lead to G31.86.
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 01 · Diseases and Disorders of the Nervous System
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2024 (effective 10/1/2023): Added
- No changes since FY2024.
Common questions about G31.86
Is G31.86 billable?
- Yes. G31.86 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can G31.86 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict G31.86 as a principal diagnosis.
Is G31.86 a CC or MCC?
- No. G31.86 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does G31.86 group to?
- G31.86 is used in the MS-DRG v44.0 logic for MS-DRG 056 (Degenerative Nervous System Disorders with MCC) and MS-DRG 057 (Degenerative Nervous System Disorders without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.