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ICD-10-CM 2027 diagnosis code

G35.C2Non-active secondary progressive multiple sclerosis

✓ Billable / specific

G35.C2 is a valid, billable ICD-10-CM code for non-active secondary progressive multiple sclerosis. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About G35.C2

G35.C2 is the ICD-10-CM diagnosis code for Non-active secondary progressive multiple sclerosis. It belongs to category G35 (multiple sclerosis), block G35-G37 (demyelinating diseases of the central nervous system) and chapter 6 (diseases of the nervous system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within G35.C (secondary progressive multiple sclerosis), G35.C2 is specifically for Non-active secondary progressive multiple sclerosis. Related codes cover unspecified (G35.C0) and active secondary progressive multiple sclerosis (G35.C1).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 058 (Multiple Sclerosis and Cerebellar Ataxia with MCC, relative weight 1.8438), DRG 059 (Multiple Sclerosis and Cerebellar Ataxia with CC, relative weight 1.2002) and DRG 060 (Multiple Sclerosis and Cerebellar Ataxia without CC/MCC, relative weight 0.9247), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2026, effective October 1, 2025.

Coding notes

Applicable toConditions and synonyms classified to this code
  • Secondary progressive multiple sclerosis without evidence of inflammatory disease activity

Notes that apply from higher levels

Instructions written at a parent level also apply to G35.C2.

Broader instructions also apply from Chapter 6: Diseases of the nervous system.

Alphabetic index entries

2 entries

Terms in the official ICD-10-CM index that lead to G35.C2.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2026 (effective 10/1/2025): Added
  • No changes since FY2026.

Common questions about G35.C2

Is G35.C2 billable?

Yes. G35.C2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can G35.C2 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict G35.C2 as a principal diagnosis.

Is G35.C2 a CC or MCC?

No. G35.C2 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does G35.C2 group to?

G35.C2 is used in the MS-DRG v44.0 logic for MS-DRG 058 (Multiple Sclerosis and Cerebellar Ataxia with MCC), MS-DRG 059 (Multiple Sclerosis and Cerebellar Ataxia with CC) and MS-DRG 060 (Multiple Sclerosis and Cerebellar Ataxia without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.