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ICD-10-CM 2027 diagnosis code

H46.3Toxic optic neuropathy

✓ Billable / specific

H46.3 is a valid, billable ICD-10-CM code for toxic optic neuropathy. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About H46.3

H46.3 is the ICD-10-CM diagnosis code for toxic optic neuropathy. It belongs to category H46 (optic neuritis), block H46-H47 (disorders of optic nerve and visual pathways) and chapter 7 (diseases of the eye and adnexa). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within H46 (optic neuritis), H46.3 is specifically for toxic optic neuropathy. Related codes cover optic papillitis (H46.0), retrobulbar neuritis (H46.1), nutritional optic neuropathy (H46.2), other optic neuritis (H46.8) and unspecified optic neuritis (H46.9).

Code first: (T51-T65) to identify cause.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 123 (Neurological Eye Disorders, relative weight 0.822), in MDC 02 (Diseases and Disorders of the Eye), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 377.34 (toxic optic neuropathy).

Coding notes

Code firstSequence the underlying condition first

Notes that apply from higher levels

Instructions written at a parent level also apply to H46.3.

› From H46 Optic neuritis
Excludes2
  • ischemic optic neuropathy (H47.01-)
  • neuromyelitis optica [Devic] (G36.0)

Broader instructions also apply from Chapter 7: Diseases of the eye and adnexa.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to H46.3.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 02 · Diseases and Disorders of the Eye

ICD-9-CM equivalent

Converter →
  • 377.34Toxic optic neuropathyexact

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about H46.3

Is H46.3 billable?

Yes. H46.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can H46.3 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict H46.3 as a principal diagnosis.

Is H46.3 a CC or MCC?

No. H46.3 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does H46.3 group to?

H46.3 is used in the MS-DRG v44.0 logic for MS-DRG 123 (Neurological Eye Disorders). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for H46.3?

The CMS General Equivalence Mappings map H46.3 to ICD-9-CM 377.34.