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ICD-10-CM 2027 diagnosis code

I25.751Atherosclerosis of native coronary artery of transplanted heart with angina pectoris with documented spasm

✓ Billable / specificCC — complication/comorbidity

I25.751 is a valid, billable ICD-10-CM code for atherosclerosis of native coronary artery of transplanted heart with angina pectoris with documented spasm. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Athscl native cor art of txplt heart w ang pctrs w spasm

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About I25.751

I25.751 is the ICD-10-CM diagnosis code for atherosclerosis of native coronary artery of transplanted heart with angina pectoris with documented spasm. It belongs to category I25 (chronic ischemic heart disease), block I20-I25 (ischemic heart diseases) and chapter 9 (diseases of the circulatory system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within I25.75 (atherosclerosis of native coronary artery of transplanted heart with angina pectoris), I25.751 is specifically for atherosclerosis of native coronary artery of transplanted heart with angina pectoris with documented spasm. Related codes cover unstable angina (I25.750), refractory angina pectoris (I25.752), other forms of angina pectoris (I25.758) and unspecified angina pectoris (I25.759).

Use an additional code to identify: chronic total occlusion of coronary artery (I25.82), exposure to environmental tobacco smoke (Z77.22), history of tobacco dependence (Z87.891), occupational exposure to environmental tobacco smoke (Z57.31), tobacco dependence (F17.-) and 1 more.

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 302 (Atherosclerosis with MCC, relative weight 1.1984) and DRG 303 (Atherosclerosis without MCC, relative weight 0.6612), in MDC 05 (Diseases and Disorders of the Circulatory System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 413.9 (other and unspecified angina pectoris) and 414.06 (coronary atherosclerosis of native coronary artery of transplanted heart).

Notes that apply from higher levels

Instructions written at a parent level also apply to I25.751.

› From I25.75 Atherosclerosis of native coronary artery of transplanted heart with angina pectoris
Excludes1
  • atherosclerosis of native coronary artery of transplanted heart without angina pectoris (I25.811)
› From I25.7 Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris
Excludes1
  • atherosclerosis of bypass graft(s) of transplanted heart without angina pectoris (I25.812)
  • atherosclerosis of coronary artery bypass graft(s) without angina pectoris (I25.810)
  • atherosclerosis of native coronary artery of transplanted heart without angina pectoris (I25.811)
Use additional code
  • code, if applicable, to identify:
  • coronary atherosclerosis due to calcified coronary lesion (I25.84)
  • coronary atherosclerosis due to lipid rich plaque (I25.83)
› From I25 Chronic ischemic heart disease
Excludes2
  • non-ischemic myocardial injury (I5A)
Use additional code
  • code to identify:
  • chronic total occlusion of coronary artery (I25.82)
  • exposure to environmental tobacco smoke (Z77.22)
  • history of tobacco dependence (Z87.891)
  • occupational exposure to environmental tobacco smoke (Z57.31)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Broader instructions also apply from I20-I25 Ischemic heart diseases and Chapter 9: Diseases of the circulatory system.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to I25.751.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 05 · Diseases and Disorders of the Circulatory System

ICD-9-CM equivalent

Converter →
  • 413.9Other and unspecified angina pectorisapproximate, combination
  • 414.06Coronary atherosclerosis of native coronary artery of transplanted heartapproximate, combination

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about I25.751

Is I25.751 billable?

Yes. I25.751 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can I25.751 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict I25.751 as a principal diagnosis.

Is I25.751 a CC or MCC?

I25.751 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does I25.751 group to?

I25.751 is used in the MS-DRG v44.0 logic for MS-DRG 302 (Atherosclerosis with MCC) and MS-DRG 303 (Atherosclerosis without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for I25.751?

The CMS General Equivalence Mappings map I25.751 to ICD-9-CM 413.9 and 414.06.