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ICD-10-CM 2027 diagnosis code

I25.752Atherosclerosis of native coronary artery of transplanted heart with refractory angina pectoris

I25.752 is a valid, billable ICD-10-CM code for atherosclerosis of native coronary artery of transplanted heart with refractory angina pectoris. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Athscl native cor art of txplt heart with refract ang pctrs

Code last changed in FY2023 (effective October 1, 2022). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About I25.752

I25.752 is the ICD-10-CM diagnosis code for atherosclerosis of native coronary artery of transplanted heart with refractory angina pectoris. It belongs to category I25 (chronic ischemic heart disease), block I20-I25 (ischemic heart diseases) and chapter 9 (diseases of the circulatory system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within I25.75 (atherosclerosis of native coronary artery of transplanted heart with angina pectoris), I25.752 is specifically for atherosclerosis of native coronary artery of transplanted heart with refractory angina pectoris. Related codes cover unstable angina (I25.750), with documented spasm (I25.751), other forms of angina pectoris (I25.758) and unspecified angina pectoris (I25.759).

Use an additional code to identify: chronic total occlusion of coronary artery (I25.82), exposure to environmental tobacco smoke (Z77.22), history of tobacco dependence (Z87.891), occupational exposure to environmental tobacco smoke (Z57.31), tobacco dependence (F17.-) and 1 more.

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 302 (Atherosclerosis with MCC, relative weight 1.1984) and DRG 303 (Atherosclerosis without MCC, relative weight 0.6612), in MDC 05 (Diseases and Disorders of the Circulatory System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

The Medicare Code Editor expects this diagnosis only for patients age 15 through 124.

It was added in FY2023, effective October 1, 2022.

Notes that apply from higher levels

Instructions written at a parent level also apply to I25.752.

› From I25.75 Atherosclerosis of native coronary artery of transplanted heart with angina pectoris
Excludes1
  • atherosclerosis of native coronary artery of transplanted heart without angina pectoris (I25.811)
› From I25.7 Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris
Excludes1
  • atherosclerosis of bypass graft(s) of transplanted heart without angina pectoris (I25.812)
  • atherosclerosis of coronary artery bypass graft(s) without angina pectoris (I25.810)
  • atherosclerosis of native coronary artery of transplanted heart without angina pectoris (I25.811)
Use additional code
  • code, if applicable, to identify:
  • coronary atherosclerosis due to calcified coronary lesion (I25.84)
  • coronary atherosclerosis due to lipid rich plaque (I25.83)
› From I25 Chronic ischemic heart disease
Excludes2
  • non-ischemic myocardial injury (I5A)
Use additional code
  • code to identify:
  • chronic total occlusion of coronary artery (I25.82)
  • exposure to environmental tobacco smoke (Z77.22)
  • history of tobacco dependence (Z87.891)
  • occupational exposure to environmental tobacco smoke (Z57.31)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Broader instructions also apply from I20-I25 Ischemic heart diseases and Chapter 9: Diseases of the circulatory system.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to I25.752.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 05 · Diseases and Disorders of the Circulatory System

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2023 (effective 10/1/2022): Added
  • No changes since FY2023.

Common questions about I25.752

Is I25.752 billable?

Yes. I25.752 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can I25.752 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict I25.752 as a principal diagnosis.

Is I25.752 a CC or MCC?

I25.752 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does I25.752 group to?

I25.752 is used in the MS-DRG v44.0 logic for MS-DRG 302 (Atherosclerosis with MCC) and MS-DRG 303 (Atherosclerosis without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.