K76.81Hepatopulmonary syndrome

K76.81 is the ICD-10-CM diagnosis code for Hepatopulmonary syndrome. It belongs to category K76 (other diseases of liver), block K70-K77 (diseases of liver) and chapter 11 (diseases of the digestive system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within K76.8 (other specified diseases of liver), K76.81 is specifically for Hepatopulmonary syndrome. Related codes cover hepatic encephalopathy (K76.82), intestinal failure-associated liver disease (K76.83) and other specified diseases of liver (K76.89).

Code first underlying liver disease, such as: alcoholic cirrhosis of liver (K70.3-) and cirrhosis of liver without mention of alcohol (K74.6-).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 205 (Other Respiratory System Diagnoses with MCC, relative weight 1.8244) and DRG 206 (Other Respiratory System Diagnoses without MCC, relative weight 0.9257), in MDC 04 (Diseases and Disorders of the Respiratory System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 573.5 (Hepatopulmonary syndrome).