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ICD-10-CM 2027 diagnosis code

E85Amyloidosis

Not billable — use a more specific code

E85 is a header code, so it can't be reported by itself. Choose one of the 7 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E85

E85 is the ICD-10-CM diagnosis code for amyloidosis. It belongs to block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 7 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: E85.0 (amyloidosis), E85.1 (amyloidosis), E85.2 (unspecified), E85.3 (amyloidosis), E85.4 (amyloidosis), E85.8 (amyloidosis) and E85.9 (unspecified).

The conditions in its Excludes2 note aren't part of E85, but may be coded alongside it if the patient has both: Alzheimer's disease (G30.0-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under E85

Coding notes

Excludes2Not included here — may be reported together if both conditions exist

Notes that apply from higher levels

Instructions written at a parent level also apply to E85.

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

Codes whose notes reference E85

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E85

Is E85 billable?

No. E85 is a header code. Report one of its more specific subcodes instead.