ICD-10-CM 2027 diagnosis code
M49.80Spondylopathy in diseases classified elsewhere, site unspecified
M49.80 is a valid, billable ICD-10-CM code for spondylopathy in diseases classified elsewhere, site unspecified. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Spondylopathy in diseases classified elsewhere, site unsp
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About M49.80
M49.80 is the ICD-10-CM diagnosis code for spondylopathy in diseases classified elsewhere, site unspecified. It belongs to category M49 (spondylopathies in diseases classified elsewhere), block M45-M49 (spondylopathies) and chapter 13 (diseases of the musculoskeletal system and connective tissue). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within M49.8, choose M49.80 (site unspecified) only when documentation doesn't support a more specific option: occipito-atlanto-axial region (M49.81), cervical region (M49.82), cervicothoracic region (M49.83), thoracic region (M49.84), thoracolumbar region (M49.85), lumbar region (M49.86), lumbosacral region (M49.87), sacral and sacrococcygeal region (M49.88) and 1 more.
Code first underlying disease, such as: brucellosis (A23.-), Charcot-Marie-Tooth disease (G60.0), enterobacterial infections (A01-A04) and osteitis fibrosa cystica (E21.0).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 551 (Medical Back Problems with MCC, relative weight 1.6358) and DRG 552 (Medical Back Problems without MCC, relative weight 0.9584), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It is a manifestation code, so it describes the effect of an underlying disease and can't be the principal diagnosis. Code the underlying condition first.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 720.81 (inflammatory spondylopathies in diseases classified elsewhere).
Notes that apply from higher levels
Instructions written at a parent level also apply to M49.80.
› From M49 Spondylopathies in diseases classified elsewhere
- curvature of spine in diseases classified elsewhere
- deformity of spine in diseases classified elsewhere
- kyphosis in diseases classified elsewhere
- scoliosis in diseases classified elsewhere
- spondylopathy in diseases classified elsewhere
- curvature of spine in tuberculosis [Pott's] (A18.01)
- enteropathic arthropathies (M07.-)
- gonococcal spondylitis (A54.41)
- neuropathic [tabes dorsalis] spondylitis (A52.11)
- neuropathic spondylopathy in syringomyelia (G95.0)
- neuropathic spondylopathy in tabes dorsalis (A52.11)
- nonsyphilitic neuropathic spondylopathy NEC (G98.0)
- spondylitis in syphilis (acquired) (A52.77)
- tuberculous spondylitis (A18.01)
- typhoid fever spondylitis (A01.05)
Broader instructions also apply from Chapter 13: Diseases of the musculoskeletal system and connective tissue.
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 08 · Diseases and Disorders of the Musculoskeletal System and Connective Tissue
ICD-9-CM equivalent
Converter →- 720.81Inflammatory spondylopathies in diseases classified elsewhereapproximate
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about M49.80
Is M49.80 billable?
- Yes. M49.80 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can M49.80 be used as a principal diagnosis?
- No. It is a manifestation code, so it describes the effect of an underlying disease and can't be the principal diagnosis. Code the underlying condition first.
Is M49.80 a CC or MCC?
- No. M49.80 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does M49.80 group to?
- M49.80 is used in the MS-DRG v44.0 logic for MS-DRG 551 (Medical Back Problems with MCC) and MS-DRG 552 (Medical Back Problems without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for M49.80?
- The CMS General Equivalence Mappings map M49.80 to ICD-9-CM 720.81.