ICD-10-CM 2027 diagnosis code
N04.22Secondary membranous nephropathy with nephrotic syndrome
N04.22 is a valid, billable ICD-10-CM code for secondary membranous nephropathy with nephrotic syndrome. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Code last changed in FY2024 (effective October 1, 2023). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About N04.22
N04.22 is the ICD-10-CM diagnosis code for secondary membranous nephropathy with nephrotic syndrome. It belongs to category N04 (nephrotic syndrome), block N00-N08 (glomerular diseases) and chapter 14 (diseases of the genitourinary system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within N04.2 (nephrotic syndrome with diffuse membranous glomerulonephritis), N04.22 is specifically for secondary membranous nephropathy with nephrotic syndrome. Related codes cover unspecified (N04.20), primary membranous nephropathy with nephrotic syndrome (N04.21) and other nephrotic syndrome with diffuse membranous glomerulonephritis (N04.29).
Code first: , if applicable, other disease or disorder or poisoning causing membranous nephropathy.
Use an additional code, if applicable, for adverse effect of drug causing membranous nephropathy.
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 698 (Other Kidney and Urinary Tract Diagnoses with MCC, relative weight 1.6398), DRG 699 (Other Kidney and Urinary Tract Diagnoses with CC, relative weight 1.0003) and DRG 700 (Other Kidney and Urinary Tract Diagnoses without CC/MCC, relative weight 0.6741), in MDC 11 (Diseases and Disorders of the Kidney and Urinary Tract), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It was added in FY2024, effective October 1, 2023.
Coding notes
- , if applicable, other disease or disorder or poisoning causing membranous nephropathy
- code, if applicable, for adverse effect of drug causing membranous nephropathy
Notes that apply from higher levels
Instructions written at a parent level also apply to N04.22.
› From N04 Nephrotic syndrome
- congenital nephrotic syndrome
- lipoid nephrosis
Broader instructions also apply from N00-N08 Glomerular diseases and Chapter 14: Diseases of the genitourinary system.
Alphabetic index entries
2 entriesTerms in the official ICD-10-CM index that lead to N04.22.
Codes whose notes reference N04.22
- N06.22Excludes1
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 11 · Diseases and Disorders of the Kidney and Urinary Tract
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2024 (effective 10/1/2023): Added
- No changes since FY2024.
Common questions about N04.22
Is N04.22 billable?
- Yes. N04.22 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can N04.22 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict N04.22 as a principal diagnosis.
Is N04.22 a CC or MCC?
- N04.22 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.
What DRG does N04.22 group to?
- N04.22 is used in the MS-DRG v44.0 logic for MS-DRG 698 (Other Kidney and Urinary Tract Diagnoses with MCC), MS-DRG 699 (Other Kidney and Urinary Tract Diagnoses with CC) and MS-DRG 700 (Other Kidney and Urinary Tract Diagnoses without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.