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ICD-10-CM 2027 diagnosis code

P59.3Neonatal jaundice from breast milk inhibitor

✓ Billable / specific

P59.3 is a valid, billable ICD-10-CM code for neonatal jaundice from breast milk inhibitor. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About P59.3

P59.3 is the ICD-10-CM diagnosis code for neonatal jaundice from breast milk inhibitor. It belongs to category P59 (neonatal jaundice from other and unspecified causes), block P50-P61 (hemorrhagic and hematological disorders of newborn) and chapter 16 (certain conditions originating in the perinatal period). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within P59 (neonatal jaundice from other and unspecified causes), P59.3 is specifically for neonatal jaundice from breast milk inhibitor. Related codes cover neonatal jaundice associated with preterm delivery (P59.0), inspissated bile syndrome (P59.1), neonatal jaundice from other and unspecified hepatocellular damage (P59.2), neonatal jaundice from other specified causes (P59.8) and neonatal jaundice, unspecified (P59.9).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 795 (Normal Newborn, relative weight 0.2022), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 774.39 (other neonatal jaundice due to delayed conjugation from other causes).

Notes that apply from higher levels

Instructions written at a parent level also apply to P59.3.

› From P59 Neonatal jaundice from other and unspecified causes
Excludes1
  • jaundice due to inborn errors of metabolism (E70-E88)
  • kernicterus (P57.-)

Broader instructions also apply from P50-P61 Hemorrhagic and hematological disorders of newborn and Chapter 16: Certain conditions originating in the perinatal period.

Alphabetic index entries

3 entries

Terms in the official ICD-10-CM index that lead to P59.3.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 15 · Newborns and Other Neonates with Conditions Originating in the Perinatal Period

ICD-9-CM equivalent

Converter →
  • 774.39Other neonatal jaundice due to delayed conjugation from other causesapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about P59.3

Is P59.3 billable?

Yes. P59.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can P59.3 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict P59.3 as a principal diagnosis.

Is P59.3 a CC or MCC?

No. P59.3 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does P59.3 group to?

P59.3 is used in the MS-DRG v44.0 logic for MS-DRG 795 (Normal Newborn). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for P59.3?

The CMS General Equivalence Mappings map P59.3 to ICD-9-CM 774.39.