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ICD-10-CM 2027 diagnosis code

QA0.014Neurodevelopmental disorders, related to pathogenic variants in synapse related genes

Not billable — use a more specific code

QA0.014 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it.Short description: Neurodev disord, rel to patho var in synapse related genes

Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About QA0.014

QA0.014 is the ICD-10-CM diagnosis code for neurodevelopmental disorders, related to pathogenic variants in synapse related genes. It belongs to category QA0 (neurodevelopmental disorders related to specific genetic pathogenic variants), block QA0-QA1 (genetic disorders, not elsewhere classified) and chapter 17 (congenital malformations, deformations, chromosomal abnormalities, and genetic disorders). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within QA0.01 (neurodevelopmental disorders related to pathogenic variants in certain specific genes), QA0.014 is specifically for neurodevelopmental disorders, related to pathogenic variants in synapse related genes. Related codes cover pathogenic variants in ion channel genes (QA0.010), pathogenic variants in glutamate receptor genes (QA0.011), pathogenic variants in other receptor genes (QA0.012), pathogenic variants in other transporter and solute carrier genes (QA0.013) and genes associated with transcription and gene expression (QA0.015).

To report this condition, pick the subcode that matches the documentation: QA0.0141 (disorder), QA0.0142 (synaptopathy) and QA0.0149 (gene).

It was added in FY2026, effective October 1, 2025.

Specific codes under QA0.014

Notes that apply from higher levels

Instructions written at a parent level also apply to QA0.014.

› From QA0 Neurodevelopmental disorders related to specific genetic pathogenic variants
Code also
  • , if applicable, any associated conditions, such as:
  • attention-deficit hyperactivity disorders (F90.-)
  • autism spectrum disorder (F84.0)
  • developmental and epileptic encephalopathy (G93.45)
  • epilepsy, by specific type (G40.-)
  • intellectual disabilities (F70-F79)
  • pervasive developmental disorders (F84.-)

Broader instructions also apply from Chapter 17: Congenital malformations, deformations, chromosomal abnormalities, and genetic disorders.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2026 (effective 10/1/2025): Added
  • No changes since FY2026.

Common questions about QA0.014

Is QA0.014 billable?

No. QA0.014 is a header code. Report one of its more specific subcodes instead.