ICD-10-CM 2027 diagnosis code
T43.5Poisoning by, adverse effect of and underdosing of other and unspecified antipsychotics and neuroleptics
T43.5 is a header code, so it can't be reported by itself. Choose one of the 2 more specific codes beneath it and add the required 7th character.Short description: And unsp antipsychotics and neuroleptics
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T43.5
T43.5 is the ICD-10-CM diagnosis code for poisoning by, adverse effect of and underdosing of other and unspecified antipsychotics and neuroleptics. It belongs to category T43 (poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.
Within T43, choose T43.5 (other and unspecified antipsychotics and neuroleptics) only when documentation doesn't support a more specific option: tricyclic and tetracyclic antidepressants (T43.0), monoamine-oxidase-inhibitor antidepressants (T43.1), other and unspecified antidepressants (T43.2), phenothiazine antipsychotics and neuroleptics (T43.3), butyrophenone and thiothixene neuroleptics (T43.4), psychostimulants (T43.6), other psychotropic drugs (T43.8) and unspecified psychotropic drug (T43.9).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
Don't report T43.5 together with the conditions in its Excludes1 note: poisoning by, adverse effect of and underdosing of rauwolfia (T46.5-).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T43
- T43.50Poisoning by, adverse effect of and underdosing of unspecified antipsychotics and neuroleptics
- T43.501Poisoning by unspecified antipsychotics and neuroleptics, accidental (unintentional)
- T43.502Poisoning by unspecified antipsychotics and neuroleptics, intentional self-harm
- T43.503Poisoning by unspecified antipsychotics and neuroleptics, assault
- T43.504Poisoning by unspecified antipsychotics and neuroleptics, undetermined
- T43.505Adverse effect of unspecified antipsychotics and neuroleptics
- T43.506Underdosing of unspecified antipsychotics and neuroleptics
- T43.59Poisoning by, adverse effect of and underdosing of other antipsychotics and neuroleptics
- T43.591Poisoning by other antipsychotics and neuroleptics, accidental (unintentional)
- T43.592Poisoning by other antipsychotics and neuroleptics, intentional self-harm
- T43.593Poisoning by other antipsychotics and neuroleptics, assault
- T43.594Poisoning by other antipsychotics and neuroleptics, undetermined
- T43.595Adverse effect of other antipsychotics and neuroleptics
- T43.596Underdosing of other antipsychotics and neuroleptics
- Ainitial encounter
- Dsubsequent encounter
- Ssequela
Coding notes
- poisoning by, adverse effect of and underdosing of rauwolfia (T46.5-)
Notes that apply from higher levels
Instructions written at a parent level also apply to T43.5.
› From T43 Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified
Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T43.5
Is T43.5 billable?
- No. T43.5 is a header code. Report one of its more specific subcodes instead.