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ICD-10-CM 2027 diagnosis code

T43.5Poisoning by, adverse effect of and underdosing of other and unspecified antipsychotics and neuroleptics

Not billable — use a more specific codeRequires 7th character

T43.5 is a header code, so it can't be reported by itself. Choose one of the 2 more specific codes beneath it and add the required 7th character.Short description: And unsp antipsychotics and neuroleptics

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About T43.5

T43.5 is the ICD-10-CM diagnosis code for poisoning by, adverse effect of and underdosing of other and unspecified antipsychotics and neuroleptics. It belongs to category T43 (poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.

Within T43, choose T43.5 (other and unspecified antipsychotics and neuroleptics) only when documentation doesn't support a more specific option: tricyclic and tetracyclic antidepressants (T43.0), monoamine-oxidase-inhibitor antidepressants (T43.1), other and unspecified antidepressants (T43.2), phenothiazine antipsychotics and neuroleptics (T43.3), butyrophenone and thiothixene neuroleptics (T43.4), psychostimulants (T43.6), other psychotropic drugs (T43.8) and unspecified psychotropic drug (T43.9).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

Don't report T43.5 together with the conditions in its Excludes1 note: poisoning by, adverse effect of and underdosing of rauwolfia (T46.5-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

7th character

The appropriate 7th character is to be added to each code from category T43

  • Ainitial encounter
  • Dsubsequent encounter
  • Ssequela

Coding notes

Excludes1Not coded here — never report together with this code
  • poisoning by, adverse effect of and underdosing of rauwolfia (T46.5-)

Notes that apply from higher levels

Instructions written at a parent level also apply to T43.5.

› From T43 Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified
Excludes2
  • appetite depressants (T50.5-)
  • barbiturates (T42.3-)
  • benzodiazepines (T42.4-)
  • drug dependence and related mental and behavioral disorders due to psychoactive substance use (F10.- -F19.-)
  • methaqualone (T42.6-)
  • psychodysleptics [hallucinogens] (T40.7-T40.9-)

Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about T43.5

Is T43.5 billable?

No. T43.5 is a header code. Report one of its more specific subcodes instead.