ICD-10-CM 2027 diagnosis code
T46.5Poisoning by, adverse effect of and underdosing of other antihypertensive drugs
T46.5 is a header code, so it can't be reported by itself. Choose one of the 1 more specific codes beneath it and add the required 7th character.Short description: Antihypertensive drugs
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T46.5
T46.5 is the ICD-10-CM diagnosis code for poisoning by, adverse effect of and underdosing of other antihypertensive drugs. It belongs to category T46 (poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 1 subcodes must be used instead.
Within T46, choose T46.5 (other antihypertensive drugs) only when documentation doesn't support a more specific option: cardiac-stimulant glycosides and drugs of similar action (T46.0), calcium-channel blockers (T46.1), other antidysrhythmic drugs, not elsewhere classified (T46.2), coronary vasodilators (T46.3), angiotensin-converting-enzyme inhibitors (T46.4), antihyperlipidemic and antiarteriosclerotic drugs (T46.6), peripheral vasodilators (T46.7), antivaricose drugs, including sclerosing agents (T46.8) and 1 more.
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
The conditions in its Excludes2 note aren't part of T46.5, but may be coded alongside it if the patient has both: poisoning by, adverse effect of and underdosing of beta-adrenoreceptor antagonists (T44.7), poisoning by, adverse effect of and underdosing of calcium-channel blockers (T46.1) and poisoning by, adverse effect of and underdosing of diuretics (T50.0-T50.2).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T46
- T46.5XPoisoning by, adverse effect of and underdosing of other antihypertensive drugs
- T46.5X1Poisoning by other antihypertensive drugs, accidental (unintentional)
- T46.5X2Poisoning by other antihypertensive drugs, intentional self-harm
- T46.5X3Poisoning by other antihypertensive drugs, assault
- T46.5X4Poisoning by other antihypertensive drugs, undetermined
- T46.5X5Adverse effect of other antihypertensive drugs
- T46.5X6Underdosing of other antihypertensive drugs
- Ainitial encounter
- Dsubsequent encounter
- Ssequela
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to T46.5.
› From T46 Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system
- poisoning by, adverse effect of and underdosing of metaraminol (T44.4)
Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Codes whose notes reference T46.5
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T46.5
Is T46.5 billable?
- No. T46.5 is a header code. Report one of its more specific subcodes instead.