ICD-10-CM 2027 diagnosis code
T49.8Poisoning by, adverse effect of and underdosing of other topical agents
T49.8 is a header code, so it can't be reported by itself. Choose one of the 1 more specific codes beneath it and add the required 7th character.Short description: Topical agents
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T49.8
T49.8 is the ICD-10-CM diagnosis code for poisoning by, adverse effect of and underdosing of other topical agents. It belongs to category T49 (poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 1 subcodes must be used instead.
Within T49, choose T49.8 (other topical agents) only when documentation doesn't support a more specific option: local antifungal, anti-infective and anti-inflammatory drugs (T49.0), antipruritics (T49.1), local astringents and local detergents (T49.2), emollients, demulcents and protectants (T49.3), keratolytics, keratoplastics, and other hair treatment drugs and preparations (T49.4), ophthalmological drugs and preparations (T49.5), otorhinolaryngological drugs and preparations (T49.6), dental drugs, topically applied (T49.7) and 1 more.
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T49
- T49.8XPoisoning by, adverse effect of and underdosing of other topical agents
- T49.8X1Poisoning by other topical agents, accidental (unintentional)
- T49.8X2Poisoning by other topical agents, intentional self-harm
- T49.8X3Poisoning by other topical agents, assault
- T49.8X4Poisoning by other topical agents, undetermined
- T49.8X5Adverse effect of other topical agents
- T49.8X6Underdosing of other topical agents
- Ainitial encounter
- Dsubsequent encounter
- Ssequela
Coding notes
- Poisoning by, adverse effect of and underdosing of spermicides
Notes that apply from higher levels
Instructions written at a parent level also apply to T49.8.
› From T49 Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs
- poisoning by, adverse effect of and underdosing of glucocorticoids, topically used
Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T49.8
Is T49.8 billable?
- No. T49.8 is a header code. Report one of its more specific subcodes instead.