ICD-10-CM 2027 diagnosis code
T49.8X5Adverse effect of other topical agents
T49.8X5 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T49.8X5
T49.8X5 is the ICD-10-CM diagnosis code for adverse effect of other topical agents. It belongs to category T49 (poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
Within T49.8X, choose T49.8X5 (Adverse effect of other topical agents) only when documentation doesn't support a more specific option: poisoning by other topical agents, accidental (unintentional) (T49.8X1), poisoning by other topical agents, intentional self-harm (T49.8X2), poisoning by other topical agents, assault (T49.8X3), poisoning by other topical agents, undetermined (T49.8X4) and underdosing of other topical agents (T49.8X6).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T49
Notes that apply from higher levels
Instructions written at a parent level also apply to T49.8X5.
› From T49 Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs
- poisoning by, adverse effect of and underdosing of glucocorticoids, topically used
Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Table of Drugs & Neoplasms entries
- Benoquin — Adverse effect
- Camphor › medicinal — Adverse effect
- Cantharides, cantharidin, cantharis — Adverse effect
- Carbamide › topical — Adverse effect
- Cell stimulants and proliferants — Adverse effect
- Charcoal › medicinal (activated) › topical — Adverse effect
- Chloresium — Adverse effect
- Contraceptive (oral) › vaginal — Adverse effect
- Cosmetic preparation — Adverse effect
- Cosmetics — Adverse effect
- Demelanizing agents — Adverse effect
- Deodorant spray (feminine hygiene) — Adverse effect
- Dextromoramide › topical — Adverse effect
- Elase — Adverse effect
- Enzyme NEC › depolymerizing — Adverse effect
- External medications (skin) (mucous membrane) › specified NEC — Adverse effect
- Gelfilm — Adverse effect
- Heet — Adverse effect
- Irrigating fluid (vaginal) — Adverse effect
- Lactic acid — Adverse effect
- Local action drug NEC — Adverse effect
- Lytta (vitatta) — Adverse effect
- Mucous membrane agents (external) › specified NEC — Adverse effect
- Nonoxinol — Adverse effect
- Nonylphenoxy (polyethoxy-ethanol) — Adverse effect
- Octoxinol (9) — Adverse effect
- Panthenol › topical — Adverse effect
- Podophyllotoxin — Adverse effect
- Preparation H — Adverse effect
- Santyl — Adverse effect
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T49.8X5
Is T49.8X5 billable?
- No. T49.8X5 is a header code. Report one of its more specific subcodes instead.