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ICD-10-CM 2027 diagnosis code

T65.22Toxic effect of tobacco cigarettes

Not billable — use a more specific codeRequires 7th character

T65.22 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it and add the required 7th character.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About T65.22

T65.22 is the ICD-10-CM diagnosis code for toxic effect of tobacco cigarettes. It belongs to category T65 (toxic effect of other and unspecified substances), block T51-T65 (toxic effects of substances chiefly nonmedicinal as to source) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.

Within T65.2 (toxic effect of tobacco and nicotine), T65.22 is specifically for toxic effect of tobacco cigarettes. Related codes cover chewing tobacco (T65.21) and other tobacco and nicotine (T65.29).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

Use an additional code for exposure to second hand tobacco smoke (Z57.31, Z77.22).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

7th character

The appropriate 7th character is to be added to each code from category T65

  • Ainitial encounter
  • Dsubsequent encounter
  • Ssequela

Coding notes

Applicable toConditions and synonyms classified to this code
  • Toxic effect of tobacco smoke
Use additional codeAdd a secondary code to fully describe the condition
  • code for exposure to second hand tobacco smoke (Z57.31, Z77.22)

Notes that apply from higher levels

Instructions written at a parent level also apply to T65.22.

› From T65.2 Toxic effect of tobacco and nicotine
Excludes2
  • nicotine dependence (F17.-)

Broader instructions also apply from T51-T65 Toxic effects of substances chiefly nonmedicinal as to source and Chapter 19: Injury, poisoning and certain other consequences of external causes.

Codes whose notes reference T65.22

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about T65.22

Is T65.22 billable?

No. T65.22 is a header code. Report one of its more specific subcodes instead.