T80.82Complication of immune effector cellular therapy

T80.82 is the ICD-10-CM diagnosis code for complication of immune effector cellular therapy. It belongs to category T80 (complications following infusion, transfusion and therapeutic injection), block T80-T88 (complications of surgical and medical care, not elsewhere classified) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within T80.8 (other complications following infusion, transfusion and therapeutic injection), T80.82 is specifically for complication of immune effector cellular therapy. Related codes cover Extravasation of vesicant agent (T80.81) and other complications following infusion, transfusion and therapeutic injection (T80.89).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

The conditions in its Excludes2 note aren't part of T80.82, but may be coded alongside it if the patient has both: adverse effect of immune checkpoint inhibitors and immunostimulant drugs (T45.AX5), complication of bone marrow transplant (T86.0) and complication of stem cell transplant (T86.5).

Use an additional code to identify the specific complication, such as: cytokine release syndrome (D89.83-) and immune effector cell-associated neurotoxicity syndrome (G92.0-).

It was added in FY2022, effective October 1, 2021.