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ICD-10-CM 2027 diagnosis code

Y64.9Contaminated medical or biological substance administered by unspecified means

✓ Billable / specific

Y64.9 is a valid, billable ICD-10-CM code for contaminated medical or biological substance administered by unspecified means. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Contaminated med/biolog sub administered by unsp means

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About Y64.9

Y64.9 is the ICD-10-CM diagnosis code for contaminated medical or biological substance administered by unspecified means. It belongs to category Y64 (contaminated medical or biological substances), block Y62-Y69 (misadventures to patients during surgical and medical care) and chapter 20 (external causes of morbidity). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within Y64, choose Y64.9 (substance administered by unspecified means) only when documentation doesn't support a more specific option: substance, transfused or infused (Y64.0), substance, injected or used for immunization (Y64.1) and substance administered by other means (Y64.8).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as E875.9 (misadventure to patient from unspecified contamination).

Coding notes

Applicable toConditions and synonyms classified to this code
  • Administered contaminated medical or biological substance NOS

Notes that apply from higher levels

Instructions written at a parent level also apply to Y64.9.

Broader instructions also apply from Y62-Y69 Misadventures to patients during surgical and medical care and Chapter 20: External causes of morbidity.

Alphabetic index entries

2 entries

Terms in the official ICD-10-CM index that lead to Y64.9.

ICD-9-CM equivalent

Converter →
  • E875.9Misadventure to patient from unspecified contaminationexact

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about Y64.9

Is Y64.9 billable?

Yes. Y64.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can Y64.9 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict Y64.9 as a principal diagnosis.

Is Y64.9 a CC or MCC?

No. Y64.9 is neither a CC nor an MCC under MS-DRG v44.0.

What is the ICD-9 code for Y64.9?

The CMS General Equivalence Mappings map Y64.9 to ICD-9-CM E875.9.