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ICD-10-CM 2027 diagnosis code

Z17.2Progesterone receptor status

Not billable — use a more specific code

Z17.2 is a header code, so it can't be reported by itself. Choose one of the 2 more specific codes beneath it.

Code last changed in FY2025 (effective October 1, 2024). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About Z17.2

Z17.2 is the ICD-10-CM diagnosis code for Progesterone receptor status. It belongs to category Z17 (estrogen, and other hormones and factors receptor status), block Z17 (estrogen, and other hormones and factors receptor status) and chapter 21 (factors influencing health status and contact with health services). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.

Within Z17 (estrogen, and other hormones and factors receptor status), Z17.2 is specifically for Progesterone receptor status. Related codes cover estrogen receptor positive status [ER+] (Z17.0), estrogen receptor negative status [ER-] (Z17.1), human epidermal growth factor 2 receptor (Z17.3) and combined receptor status (Z17.4).

To report this condition, pick the subcode that matches the documentation: Z17.21 (status) and Z17.22 (status).

Code first malignant neoplasm, such as: malignant neoplasm of breast (C50.-) and malignant neoplasm of ovary (C56.-).

It was added in FY2025, effective October 1, 2024.

Specific codes under Z17.2

Notes that apply from higher levels

Instructions written at a parent level also apply to Z17.2.

› From Z17 Estrogen, and other hormones and factors receptor status
Note
Code first
  • malignant neoplasm, such as:
  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of ovary (C56.-)

Broader instructions also apply from Chapter 21: Factors influencing health status and contact with health services.

Codes whose notes reference Z17.2

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2025 (effective 10/1/2024): Added
  • No changes since FY2025.

Common questions about Z17.2

Is Z17.2 billable?

No. Z17.2 is a header code. Report one of its more specific subcodes instead.