ICD-10-CM 2027 diagnosis code
C50Malignant neoplasm of breast
C50 is a header code, so it can't be reported by itself. Choose one of the 10 more specific codes beneath it.
Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS, effective October 1, 2026. Updated September 29, 2026. About our data
About C50
C50 is the ICD-10-CM diagnosis code for malignant neoplasm of breast. It belongs to block C50 (malignant neoplasms of breast) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 10 subcodes must be used instead.
To report this condition, pick the subcode that matches the documentation: C50.0 (areola), C50.1 (breast), C50.2 (breast), C50.3 (breast), C50.4 (breast), C50.5 (breast), C50.6 (breast), C50.8 (breast) and 2 more.
Don't report C50 together with the conditions in its Excludes1 note: skin of breast (C44.501, C44.511, C44.521, C44.591).
Use an additional code to identify estrogen, and other hormones and factors receptor status (Z17.-).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under C50
- C50.0Malignant neoplasm of nipple and areola
- C50.1Malignant neoplasm of central portion of breast
- C50.2Malignant neoplasm of upper-inner quadrant of breast
- C50.3Malignant neoplasm of lower-inner quadrant of breast
- C50.4Malignant neoplasm of upper-outer quadrant of breast
- C50.5Malignant neoplasm of lower-outer quadrant of breast
- C50.6Malignant neoplasm of axillary tail of breast
- C50.8Malignant neoplasm of overlapping sites of breast
- C50.9Malignant neoplasm of breast of unspecified site
- C50.AMalignant inflammatory neoplasm of breast
Coding notes
- connective tissue of breast
- Paget's disease of breast
- Paget's disease of nipple
- code to identify estrogen, and other hormones and factors receptor status (Z17.-)
Notes that apply from higher levels
Instructions written at a parent level also apply to C50.
Broader instructions also apply from Chapter 2: Neoplasms.
Codes whose notes reference C50
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about C50
Is C50 billable?
- No. C50 is a header code. Report one of its more specific subcodes instead.