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ICD-10-CM 2027 diagnosis code

C50Malignant neoplasm of breast

Not billable — use a more specific code

C50 is a header code, so it can't be reported by itself. Choose one of the 10 more specific codes beneath it.

Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS, effective October 1, 2026. Updated September 29, 2026. About our data

About C50

C50 is the ICD-10-CM diagnosis code for malignant neoplasm of breast. It belongs to block C50 (malignant neoplasms of breast) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 10 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: C50.0 (areola), C50.1 (breast), C50.2 (breast), C50.3 (breast), C50.4 (breast), C50.5 (breast), C50.6 (breast), C50.8 (breast) and 2 more.

Don't report C50 together with the conditions in its Excludes1 note: skin of breast (C44.501, C44.511, C44.521, C44.591).

Use an additional code to identify estrogen, and other hormones and factors receptor status (Z17.-).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under C50

Coding notes

IncludesFurther defines the content of the category
  • connective tissue of breast
  • Paget's disease of breast
  • Paget's disease of nipple
Excludes1Not coded here — never report together with this code
Use additional codeAdd a secondary code to fully describe the condition
  • code to identify estrogen, and other hormones and factors receptor status (Z17.-)

Notes that apply from higher levels

Instructions written at a parent level also apply to C50.

Broader instructions also apply from Chapter 2: Neoplasms.

Codes whose notes reference C50

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about C50

Is C50 billable?

No. C50 is a header code. Report one of its more specific subcodes instead.