ICD-10-CM 2027 diagnosis code
Z22.7Latent tuberculosis
Z22.7 is a valid, billable ICD-10-CM code for latent tuberculosis. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Looking up by condition? See ICD-10 code for LTBI.
Code last changed in FY2020 (effective October 1, 2019). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About Z22.7
Z22.7 is the ICD-10-CM diagnosis code for latent tuberculosis. It belongs to category Z22 (carrier of infectious disease), block Z20-Z29 (persons with potential health hazards related to communicable diseases) and chapter 21 (factors influencing health status and contact with health services). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within Z22 (carrier of infectious disease), Z22.7 is specifically for latent tuberculosis. Related codes cover carrier of typhoid (Z22.0), carrier of other intestinal infectious diseases (Z22.1), carrier of diphtheria (Z22.2), carrier of other specified bacterial diseases (Z22.3), carrier of infections with a predominantly sexual mode of transmission (Z22.4), carrier of human T-lymphotropic virus type-1 [HTLV-1] infection (Z22.6), carrier of other infectious diseases (Z22.8) and unspecified (Z22.9).
Don't report Z22.7 together with the conditions in its Excludes1 note: nonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis (R76.12) and nonspecific reaction to tuberculin skin test without active tuberculosis (R76.11).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 951 (Other Factors Influencing Health Status, relative weight 0.5577), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
It is exempt from present-on-admission (POA) reporting, so no POA indicator is required.
It was added in FY2020, effective October 1, 2019.
Coding notes
- Latent tuberculosis infection (LTBI)
Notes that apply from higher levels
Instructions written at a parent level also apply to Z22.7.
› From Z22 Carrier of infectious disease
- colonization status
- suspected carrier
- carrier of viral hepatitis (B18.-)
Broader instructions also apply from Chapter 21: Factors influencing health status and contact with health services.
Alphabetic index entries
4 entriesTerms in the official ICD-10-CM index that lead to Z22.7.
- Infection, infected, infective (opportunistic) › tuberculous › latent (LTBI)
- LTBI (latent tuberculosis infection)
- Tuberculosis, tubercular, tuberculous (calcification) (calcified) (caseous) (chromogenic acid-fast bacilli) (degeneration) (fibrocaseous) (fistula) (interstitial) (isolated circumscribed lesions) (necrosis) (parenchymatous) (ulcerative) › abscess (respiratory) › latent
- Tuberculosis, tubercular, tuberculous (calcification) (calcified) (caseous) (chromogenic acid-fast bacilli) (degeneration) (fibrocaseous) (fistula) (interstitial) (isolated circumscribed lesions) (necrosis) (parenchymatous) (ulcerative) › latent
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 23 · Factors Influencing Health Status and Other Contacts with Health Services
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2020 (effective 10/1/2019): Added
- No changes since FY2020.
Common questions about Z22.7
Is Z22.7 billable?
- Yes. Z22.7 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Z22.7 be used as a principal diagnosis?
- No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
Is Z22.7 a CC or MCC?
- No. Z22.7 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does Z22.7 group to?
- Z22.7 is used in the MS-DRG v44.0 logic for MS-DRG 951 (Other Factors Influencing Health Status). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.