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ICD-10-CM 2027 diagnosis code

Z80.4Family history of malignant neoplasm of genital organs

Not billable — use a more specific code

Z80.4 is a header code, so it can't be reported by itself. Choose one of the 5 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About Z80.4

Z80.4 is the ICD-10-CM diagnosis code for family history of malignant neoplasm of genital organs. It belongs to category Z80 (family history of primary malignant neoplasm), block Z77-Z99 (persons with potential health hazards related to family and personal history and certain conditions influencing health status) and chapter 21 (factors influencing health status and contact with health services). It is a header code, so it can't be reported by itself; one of its 5 subcodes must be used instead.

Within Z80 (family history of primary malignant neoplasm), Z80.4 is specifically for family history of malignant neoplasm of genital organs. Related codes cover malignant neoplasm of digestive organs (Z80.0), malignant neoplasm of trachea, bronchus and lung (Z80.1), malignant neoplasm of other respiratory and intrathoracic organs (Z80.2), malignant neoplasm of breast (Z80.3), malignant neoplasm of urinary tract (Z80.5), leukemia (Z80.6), other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z80.7), malignant neoplasm of other organs or systems (Z80.8) and 1 more.

To report this condition, pick the subcode that matches the documentation: Z80.41 (ovary), Z80.42 (prostate), Z80.43 (testis), Z80.44 (tube(s)) and Z80.49 (organs).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under Z80.4

Coding notes

Applicable toConditions and synonyms classified to this code
  • Conditions classifiable to C51-C63

Notes that apply from higher levels

Instructions written at a parent level also apply to Z80.4.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about Z80.4

Is Z80.4 billable?

No. Z80.4 is a header code. Report one of its more specific subcodes instead.