ICD-10-CM 2027 diagnosis code
Z80.8Family history of malignant neoplasm of other organs or systems
Z80.8 is a valid, billable ICD-10-CM code for family history of malignant neoplasm of other organs or systems. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Family history of malignant neoplasm of organs or systems
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About Z80.8
Z80.8 is the ICD-10-CM diagnosis code for family history of malignant neoplasm of other organs or systems. It belongs to category Z80 (family history of primary malignant neoplasm), block Z77-Z99 (persons with potential health hazards related to family and personal history and certain conditions influencing health status) and chapter 21 (factors influencing health status and contact with health services). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within Z80, choose Z80.8 (malignant neoplasm of other organs or systems) only when documentation doesn't support a more specific option: malignant neoplasm of digestive organs (Z80.0), malignant neoplasm of trachea, bronchus and lung (Z80.1), malignant neoplasm of other respiratory and intrathoracic organs (Z80.2), malignant neoplasm of breast (Z80.3), malignant neoplasm of genital organs (Z80.4), malignant neoplasm of urinary tract (Z80.5), leukemia (Z80.6), other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z80.7) and 1 more.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 951 (Other Factors Influencing Health Status, relative weight 0.5577), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
It is exempt from present-on-admission (POA) reporting, so no POA indicator is required.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as V16.8 (family history of other specified malignant neoplasm).
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to Z80.8.
Alphabetic index entries
1 entriesTerms in the official ICD-10-CM index that lead to Z80.8.
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 23 · Factors Influencing Health Status and Other Contacts with Health Services
ICD-9-CM equivalent
Converter →- V16.8Family history of other specified malignant neoplasmexact
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about Z80.8
Is Z80.8 billable?
- Yes. Z80.8 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Z80.8 be used as a principal diagnosis?
- No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
Is Z80.8 a CC or MCC?
- No. Z80.8 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does Z80.8 group to?
- Z80.8 is used in the MS-DRG v44.0 logic for MS-DRG 951 (Other Factors Influencing Health Status). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.