ICD-10-CM 2027
ICD-10 code for Acromegaly
From the official ICD-10-CM alphabetic index entry “Acromegaly, acromegalia”. Page updated September 29, 2026.
About coding Acromegaly
The ICD-10-CM code for Acromegaly is E22.0 (Acromegaly and pituitary gigantism).
Within E22 (hyperfunction of pituitary gland), E22.0 is specifically for Acromegaly and pituitary gigantism. Related codes cover Hyperprolactinemia (E22.1), syndrome of inappropriate secretion of antidiuretic hormone (E22.2), other hyperfunction of pituitary gland (E22.8) and unspecified (E22.9).
Don't report E22.0 together with the conditions in its Excludes1 note: constitutional gigantism (E34.4), constitutional tall stature (E34.4) and increased secretion from endocrine pancreas of growth hormone-releasing hormone (E16.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Don't confuse with (Excludes1 for E22.0)
Common questions about Acromegaly ICD-10 codes
What is the ICD-10 code for Acromegaly?
- E22.0 — Acromegaly and pituitary gigantism.
Is E22.0 billable?
- Yes. E22.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E22.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E22.0 as a principal diagnosis.
Is E22.0 a CC or MCC?
- No. E22.0 is neither a CC nor an MCC under MS-DRG v44.0.