ICD-10-CM 2027
ICD-10 code for acute megakaryocytic leukemia
From the official ICD-10-CM alphabetic index entry “Leukemia, leukemic › acute megakaryocytic”. Page updated September 29, 2026.
About coding acute megakaryocytic leukemia
The ICD-10-CM code for acute megakaryocytic leukemia is C94.2 (Acute megakaryoblastic leukemia).
Within C94 (other leukemias of specified cell type), C94.2 is specifically for acute megakaryoblastic leukemia. Related codes cover acute erythroid leukemia (C94.0), mast cell leukemia (C94.3), acute panmyelosis with myelofibrosis (C94.4), myelodysplastic disease, not elsewhere classified (C94.6) and other specified leukemias (C94.8).
To report this condition, pick the subcode that matches the documentation: C94.20 (not having achieved remission), C94.21 (in remission) and C94.22 (in relapse).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.