C94.4Acute panmyelosis with myelofibrosis

C94.4 is the ICD-10-CM diagnosis code for acute panmyelosis with myelofibrosis. It belongs to category C94 (other leukemias of specified cell type), block C81-C96 (malignant neoplasms of lymphoid, hematopoietic and related tissue) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within C94 (other leukemias of specified cell type), C94.4 is specifically for acute panmyelosis with myelofibrosis. Related codes cover acute erythroid leukemia (C94.0), acute megakaryoblastic leukemia (C94.2), mast cell leukemia (C94.3), myelodysplastic disease, not elsewhere classified (C94.6) and other specified leukemias (C94.8).

To report this condition, pick the subcode that matches the documentation: C94.40 (not having achieved remission), C94.41 (in remission) and C94.42 (in relapse).

Don't report C94.4 together with the conditions in its Excludes1 note: myelofibrosis NOS (D75.81) and secondary myelofibrosis NOS (D75.81).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.