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ICD-10-CM 2027 diagnosis code

C94.6Myelodysplastic disease, not elsewhere classified

✓ Billable / specificCC — complication/comorbidity

C94.6 is a valid, billable ICD-10-CM code for myelodysplastic disease, not elsewhere classified. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code last changed in FY2023 (effective October 1, 2022). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About C94.6

C94.6 is the ICD-10-CM diagnosis code for myelodysplastic disease, not elsewhere classified. It belongs to category C94 (other leukemias of specified cell type), block C81-C96 (malignant neoplasms of lymphoid, hematopoietic and related tissue) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within C94 (other leukemias of specified cell type), C94.6 is specifically for myelodysplastic disease, not elsewhere classified. Related codes cover acute erythroid leukemia (C94.0), acute megakaryoblastic leukemia (C94.2), mast cell leukemia (C94.3), acute panmyelosis with myelofibrosis (C94.4) and other specified leukemias (C94.8).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC, relative weight 6.2481), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC, relative weight 2.2023), DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC, relative weight 1.1272), DRG 823 (Lymphoma and Non-Acute Leukemia with Other Procedures with MCC, relative weight 4.6059), DRG 824 (Lymphoma and Non-Acute Leukemia with Other Procedures with CC, relative weight 2.2515), DRG 825 (Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC, relative weight 1.2995) and 3 more, in MDC 17 (Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2023 (title revised).

Before ICD-10, this condition was coded in ICD-9-CM as 238.79 (other lymphatic and hematopoietic tissues).

Coding notes

Applicable toConditions and synonyms classified to this code
  • Myelodysplastic/myeloproliferative neoplasm, unclassifiable
  • Myeloproliferative disease, not elsewhere classified

Notes that apply from higher levels

Instructions written at a parent level also apply to C94.6.

› From C94 Other leukemias of specified cell type
Excludes1
  • leukemic reticuloendotheliosis (C91.4-)
  • myelodysplastic syndromes (D46.-)
  • personal history of leukemia (Z85.6)
  • plasma cell leukemia (C90.1-)

Broader instructions also apply from C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue and Chapter 2: Neoplasms.

Alphabetic index entries

6 entries

Terms in the official ICD-10-CM index that lead to C94.6.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 238.79Other lymphatic and hematopoietic tissuesapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • FY2023 (effective 10/1/2022): Title revised — was “Myelodysplastic disease, not classified”

Common questions about C94.6

Is C94.6 billable?

Yes. C94.6 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can C94.6 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict C94.6 as a principal diagnosis.

Is C94.6 a CC or MCC?

C94.6 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does C94.6 group to?

C94.6 is used in the MS-DRG v44.0 logic for MS-DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC), MS-DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC), MS-DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC), MS-DRG 823 (Lymphoma and Non-Acute Leukemia with Other Procedures with MCC), MS-DRG 824 (Lymphoma and Non-Acute Leukemia with Other Procedures with CC), MS-DRG 825 (Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC) and 3 more. Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for C94.6?

The CMS General Equivalence Mappings map C94.6 to ICD-9-CM 238.79.